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13mm & 20mm Pharmaceutical Butyl Rubber Stopper – Medical-Grade Closure for Glass Vials

High-Quality, Self-Healing Rubber Stoppers for Injectable Medications and Biopharmaceuticals

Designed for use in pharmaceutical primary packaging, the 13mm and 20mm Butyl Rubber Stopper from PharGlass provides a reliable, sterile-seal closure solution for glass vials containing injectable drugs, vaccines, biologics, and lyophilized products. Crafted from medical-grade butyl rubber, these stoppers feature self-healing properties that ensure a tight seal after needle penetration — minimizing product leakage and contamination risk.

Available in multiple sizes (13mm, 20mm, 26mm, 28mm, 32mm), with customizable colors (gray, red, or per customer request), this high-performance rubber plug is ideal for both OEM and ODM applications in the global pharmaceutical industry.

Manufactured in Henan, China, under ISO 9001:2008 / ISO 14001:2004 / OHSAS 18001:1999 certified facilities, our stoppers meet international standards including USP <661>, EP 3.1.9, JP XVII, and FDA 21 CFR 177.1520, ensuring compliance with global regulatory requirements.

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✅ Key Features:

Feature	Description
Material	Medical-grade Butyl Rubber (Bromobutyl or Chlorobutyl available)
Self-Healing Design	Re-seals automatically after needle puncture, preventing leakage
Low Extractables	Minimizes leachables and extractables to protect sensitive formulations
Excellent Seal Integrity	Ensures long-term protection against moisture and microbial ingress
Customizable Sizes	Available in 13mm, 20mm, 26mm, 28mm, 32mm
Color Options	Gray, Red, or Custom (based on client specification)
OEM/ODM Support	Yes – custom size, color, surface treatment, logo printing
Free Sample Policy	Free samples available for quality evaluation

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Product Specifications

Parameter	Specification
Product Name	13mm 20mm Rubber Plug Pharmaceutical Rubber Stopper
Model Number	03
Brand Name	PharGlass
Material	Butyl Rubber (Bromobutyl or Chlorobutyl optional)
Color	Gray, Red, or Customer Request
Size Options	13mm, 20mm, 26mm, 28mm, 32mm
Place of Origin	Henan, China
Usage	Primary packaging for glass vials (injectables, biologics, vaccines)
Processing Service	Moulding
Packaging	Plastic Bag + Carton
MOQ	10,000 pcs
Sample Availability	Free Samples
OEM/ODM Support	Acceptable
Feature	Medical Grade, Self-Healing, Low Extractables
Single Package Size	10×20×15 cm
Gross Weight	1.000 kg per unit
Standards Compliance	ISO 9001:2008, ISO 14001:2004, OHSAS 18001:1999
Regulatory Standards	USP <661>, EP 3.1.9, JP XVII, FDA 21 CFR 177.1520

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Technical Insights & Industry Applications

🔬 Why Choose Butyl Rubber Stoppers?

Butyl rubber is widely recognized in the pharmaceutical industry for its:

• Exceptional impermeability to gases (especially oxygen and water vapor)
• Low permeation rate, ideal for long-term storage
• Good elasticity and resilience, ensuring consistent sealing performance

According to research published in Journal of Pharmaceutical Sciences, butyl rubber stoppers significantly reduce drug degradation caused by oxidation, especially in sterile injectable solutions y lyophilized powders.

Note: For freeze-dried (lyophilized) products, we recommend chlorobutyl rubber due to its superior moisture barrier y low extractables profile.

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Ideal Applications:

✅ Pharmaceutical Packaging

• Injectable medications (e.g., insulin, monoclonal antibodies)
• Vaccines and biologics
• Lyophilized (freeze-dried) products
• Pre-filled syringe systems

✅ Biotechnology & Research

• Lab sample storage
• Stability testing vials
• Clinical trial packaging

✅ Cosmetics & Aromatherapy (with non-injectable use)

• High-end essential oil bottles
• Premium skincare serums

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¿Por qué elegir PharGlass?

En PharGlass, we specialize in providing customized, high-quality primary packaging solutions for the global pharmaceutical and cosmetic markets. Our rubber stoppers are manufactured using advanced molding technology and undergo strict quality control, including:

• Extractables & Leachables (E&L) testing
• Visual inspection (no defects)
• Seal integrity and puncture resistance testing
• COA, DMF, and TDS documentation support

We offer full OEM/ODM services, including:

• Custom sizing and shape
• Logo printing via hot stamping or silk screen
• COA and technical data sheet (TDS) provision
• Fast sample delivery within 3–5 days

Whether you’re developing a new biologic drug or launching a premium skincare line, our medical-grade rubber stoppers ensure your product remains protected, stable, and compliant.

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📞 Contact Us Today
For pricing, technical documentation, or custom design requests — reach out to our sales team at sales@pharglass.com or visit https://www.pharglass.com.

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Note: All products are produced under cleanroom conditions and can be sterilized via gamma irradiation or autoclave upon request. We recommend chlorobutyl rubber for freeze-dried applications and butyl rubber for general injectables.

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