{"id":1268,"date":"2026-02-04T06:06:21","date_gmt":"2026-02-04T06:06:21","guid":{"rendered":"https:\/\/www.pharglass.com\/?p=1268"},"modified":"2026-02-06T05:50:54","modified_gmt":"2026-02-06T05:50:54","slug":"13mm-20mm-butyl-rubber-stopper-rubber-self-healing-injection-ports-solid-seal-for-glass-vial-liquid","status":"publish","type":"post","link":"https:\/\/www.pharglass.com\/pt\/13mm-20mm-butyl-rubber-stopper-rubber-self-healing-injection-ports-solid-seal-for-glass-vial-liquid\/","title":{"rendered":"Tampa de borracha but\u00edlica de 13 mm e 20 mm Portas de inje\u00e7\u00e3o autocicatrizantes de borracha Selo s\u00f3lido para frasco de vidro l\u00edquido"},"content":{"rendered":"
\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n<\/figure>\n\n\n\n
\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n<\/figure>\n\n\n\n
\n\n\n\n

13mm & 20mm Butyl Rubber Stopper with Self-Healing Injection Port \u2013 Medical-Grade Solid Seal for Glass Vials<\/strong><\/h1>\n\n\n\n

Premium Self-Healing Rubber Stopper<\/strong> with Dual-Lip Design \u2013 Ideal for Injectables, Vaccines, and Biologics<\/strong> in Type I Borosilicate Glass Vials<\/strong><\/h2>\n\n\n\n

O 13mm and 20mm Butyl Rubber Stopper with Self-Healing Injection Port<\/strong> from PharGlass<\/strong> is engineered to deliver superior seal integrity<\/strong>, low extractables<\/strong>, e reliable resealing performance<\/strong> after needle penetration. Designed specifically for use in pharmaceutical glass vials<\/strong>, this medical-grade rubber closure<\/strong> features a dual-lip (U-shaped) structure<\/strong> that ensures tight sealing against moisture, oxygen, and microbial ingress \u2014 making it ideal for sterile injectable drugs<\/strong>, mRNA vaccines<\/strong>, e lyophilized biologics<\/strong>.<\/p>\n\n\n\n

This solid seal stopper<\/strong> is widely used in multi-dose vials<\/strong> where repeated access via syringe is required. Its self-healing property<\/strong> allows the rubber to close automatically after needle withdrawal, minimizing product leakage and contamination risk \u2014 a critical feature supported by USP<\/strong> e EP 3.1.9<\/strong> padr\u00f5es.<\/p>\n\n\n\n

Manufactured under ISO 9001:2015<\/strong> e GMP-compliant<\/strong> conditions in Henan, China, every stopper undergoes rigorous quality control, including extractables testing<\/strong>, visual inspection<\/strong>, e bioburden analysis<\/strong>, ensuring full compliance with global pharmaceutical regulations.<\/p>\n\n\n\n

\n\n\n\n

Principais recursos:<\/h3>\n\n\n\n
Recurso<\/th>Descri\u00e7\u00e3o<\/th><\/tr><\/thead>
Material<\/strong><\/td>Medical-grade Butyl Rubber<\/strong>, Bromobutyl<\/strong>, or Chlorobutyl<\/strong> (optional)<\/td><\/tr>
Design Type<\/strong><\/td>Dual-lip \/ U-shaped injection port<\/strong> \u2013 enhances puncture resistance and self-sealing<\/td><\/tr>
Self-Healing Technology<\/strong><\/td>Automatically reseals after needle removal; prevents leakage<\/td><\/tr>
Low Extractables<\/strong><\/td>Minimizes leachables that could affect drug stability or safety<\/td><\/tr>
Moisture Barrier<\/strong><\/td>Excellent protection against humidity ingress<\/td><\/tr>
Customizable Sizes<\/strong><\/td>Available in 13mm, 20mm, 26mm, 28mm, 32mm<\/strong><\/td><\/tr>
Op\u00e7\u00f5es de cores<\/strong><\/td>Gray, Red, or Customer Request<\/td><\/tr>
Suporte a OEM\/ODM<\/strong><\/td>Yes \u2013 custom size, color, logo printing, surface treatment<\/td><\/tr>
Free Sample Policy<\/strong><\/td>Free samples available for compatibility testing<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
\n\n\n\n

Technical Specifications: 13mm & 20mm Self-Healing Rubber Stopper<\/strong><\/h2>\n\n\n\n
Par\u00e2metro<\/strong><\/th>Especifica\u00e7\u00e3o<\/strong><\/th><\/tr><\/thead>
Nome do produto<\/strong><\/td>13mm 20mm Butyl Rubber Stopper with Self-Healing Injection Port<\/td><\/tr>
N\u00famero do modelo<\/strong><\/td>03<\/td><\/tr>
Nome da marca<\/strong><\/td>PharGlass<\/strong><\/td><\/tr>
Material<\/strong><\/td>Butyl Rubber<\/strong>, Bromobutyl Rubber<\/strong>, Chlorobutyl Rubber<\/strong><\/td><\/tr>
Cor<\/strong><\/td>Gray, Red, or Custom<\/td><\/tr>
Sizes Available<\/strong><\/td>13 mm<\/strong>, 20 mm<\/strong>, 26mm, 28mm, 32mm<\/td><\/tr>
Local de origem<\/strong><\/td>Henan, China<\/td><\/tr>
Uso<\/strong><\/td>Primary closure for glass vials<\/strong> (injectables, vaccines, biologics)<\/td><\/tr>
Servi\u00e7o de processamento<\/strong><\/td>Precision compression molding<\/td><\/tr>
Embalagem<\/strong><\/td>Plastic Bag + Export Carton<\/td><\/tr>
MOQ<\/strong><\/td>10.000 unidades<\/td><\/tr>
Sample Availability<\/strong><\/td>Free Samples<\/td><\/tr>
Suporte a OEM\/ODM<\/strong><\/td>Aceit\u00e1vel<\/td><\/tr>
Recurso<\/strong><\/td>Medical Grade<\/strong>, Self-Healing<\/strong>, Solid Seal<\/strong>, Low Extractables<\/strong><\/td><\/tr>
Tamanho da embalagem \u00fanica<\/strong><\/td>10\u00d720\u00d715 cm<\/td><\/tr>
Peso bruto<\/strong><\/td>1.000 kg por unidade<\/td><\/tr>
Certifica\u00e7\u00f5es<\/strong><\/td>ISO 9001:2015<\/strong>, ISO 14001<\/strong>, OHSAS 18001<\/strong><\/td><\/tr>
Conformidade regulat\u00f3ria<\/strong><\/td>USP<\/strong>, EP 3.1.9<\/strong>, JP XVII<\/strong>, FDA 21 CFR 177.1520<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
\n\n\n\n

Why This Design Matters: The Science Behind the Dual-Lip Structure<\/strong><\/h2>\n\n\n\n

O U-shaped (or dual-lip)<\/strong> design of this rubber stopper<\/strong> is not just aesthetic \u2014 it\u2019s a functional innovation<\/strong> that improves performance in several key areas:<\/p>\n\n\n\n

\ud83d\udd39 Enhanced Puncture Resistance<\/strong>: The two raised lips distribute needle pressure evenly, reducing deformation and improving durability during multiple withdrawals.
\ud83d\udd39 Improved Re-Sealability<\/strong>: After needle withdrawal, the elastic rubber returns to its original shape, forming a tight seal<\/strong> without gaps.
\ud83d\udd39 Reduced Risk of Product Loss<\/strong>: Critical for high-cost biologics<\/strong> e vaccines<\/strong>, where even minor leakage can lead to waste or contamination.<\/p>\n\n\n\n

According to a study published in Jornal de Ci\u00eancias Farmac\u00eauticas<\/em> (2021), U-shaped stoppers reduce leakage rates by up to 40%<\/strong> compared to flat-faced designs in multi-dose applications.<\/p>\n\n\n\n

\n\n\n\n

Material Comparison: Which Rubber Is Right for Your Formulation?<\/strong><\/h2>\n\n\n\n
Rubber Type<\/strong><\/th>Best For<\/strong><\/th>Key Advantages<\/strong><\/th><\/tr><\/thead>
Butyl Rubber<\/strong><\/td>General injectables, liquid formulations<\/td>Cost-effective, good elasticity, low gas permeability<\/td><\/tr>
Bromobutyl Rubber<\/strong><\/td>Vacinas<\/strong>, biologics<\/strong>, multi-dose vials<\/strong><\/td>Enhanced chemical resistance, better adhesion to aluminum seals<\/td><\/tr>
Chlorobutyl Rubber<\/strong><\/td>Lyophilized (freeze-dried) products<\/strong><\/td>Superior moisture barrier<\/strong>, lowest extractables profile<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
\n

Observa\u00e7\u00e3o<\/strong>: For freeze-dried (lyophilized)<\/strong> products, we recommend chlorobutyl rubber<\/strong> due to its excellent moisture barrier properties<\/strong> e low extractables<\/strong>, as confirmed by studies in European Journal of Pharmaceutics<\/em>.<\/p>\n<\/blockquote>\n\n\n\n

\n\n\n\n

Top Applications in Pharma & Biotech<\/strong><\/h2>\n\n\n\n