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13mm & 20mm Silicone Rubber Stopper – High-Performance Seal for Essential Oils, Pharmaceuticals & Freeze-Dried Products

Medical-Grade Silicone & Butyl Rubber Stoppers with Self-Healing Properties for Glass Vials

Designed for precision sealing in both pharmaceutical packaging y high-end essential oil applications, our 13mm and 20mm silicone rubber stoppers offer superior chemical resistance, low extractables, and excellent self-healing capabilities after needle penetration. These solid seal injection ports are ideal for use in glass vials containing injectable drugs, vaccines, biologics, or premium essential oils.

Available in white silicone, butyl rubber, and chlorobutyl rubber variants, these stoppers provide a reliable barrier against moisture, oxidation, and contamination — ensuring product stability and shelf-life integrity. Whether you’re packaging freeze-dried lyophilized products, sterile injectables, or aromatherapy blends, our stoppers deliver consistent performance under demanding conditions.

Manufactured in Henan, China, under ISO 9001:2008 / ISO 14001:2004 / OHSAS 18001:1999 certified facilities, these stoppers meet international standards including USP <661>, EP 3.1.9, and JP XVII, making them suitable for global regulatory compliance.

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✅ Key Features:

Feature	Description
Material Options	White Silicone, Butyl Rubber, Chlorobutyl Rubber (CB)
Self-Healing Design	Re-seals automatically after needle puncture, minimizing leakage risk
Low Extractables	Minimizes leachables and extractables to protect sensitive formulations
Chemical Resistance	Resistant to acids, bases, solvents, and essential oil components
Moisture Barrier	Excellent protection against humidity ingress
Customizable Sizes	Available in 13mm, 15mm, 20mm, 25mm, 28mm, 30mm
Color Options	Red, Gray, White (depending on material)
OEM/ODM Support	Yes – custom design, size, color, surface treatment available
Free Sample Policy	Free samples for quality evaluation

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Product Specifications

Parameter	Specification
Product Name	13mm 20mm Butyl Rubber Stopper / Silicone Rubber Stopper for Glass Vial Liquid
Material	Butyl Rubber, Bromobutyl Rubber, Chlorobutyl Rubber, White Silicone
Function	Primary closure for glass vials; self-healing injection port
Size Options	13mm, 15mm, 20mm, 25mm, 28mm, 30mm
Color	Red, Gray (rubber), White (silicone)
Place of Origin	Henan, China
Brand Name	PharGlass
Package	Carton
MOQ	10,000 pcs
Surface Handling	Hot stamping, embossing, logo printing
Standards Compliance	ISO 9001:2008, ISO 14001:2004, OHSAS 18001:1999
Regulatory Standards	USP <661>, EP 3.1.9, JP XVII, FDA 21 CFR 177.1520
Usage	Injectable medicines, vaccines, biologics, freeze-dried products, essential oils
Industrial Use	Pharmaceutical, Cosmetic, Biotech, Aromatherapy
Sample Availability	Free samples upon request

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Technical Insights & Material Comparison

🔬 Why Choose the Right Rubber Type?

Material	Best For	Key Advantages
White Silicone	Essential oils, aromatherapy, non-injectable liquids	Non-reactive, odorless, excellent flexibility, ideal for volatile compounds
Butyl Rubber	General pharmaceuticals, sterile injectables	Low permeability to gases, good elasticity, moderate cost
Chlorobutyl Rubber (CB)	Freeze-dried products, high-purity injectables	Superior chemical resistance, lower extractables, ideal for lyophilization

Note: Chlorobutyl rubber is particularly recommended for lyophilized (freeze-dried) products due to its excellent moisture barrier properties y low extractables profile, as confirmed by studies in Journal of Pharmaceutical Sciences y European Journal of Pharmaceutics.

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Ideal Applications:

✅ Pharmaceutical Industry

• Injectable drugs (e.g., insulin, monoclonal antibodies)
• Vaccines and biologics
• Lyophilized (freeze-dried) powders
• Pre-filled syringe systems

✅ Cosmetics & Aromatherapy

• Premium essential oil bottles
• Custom fragrance samples
• Natural skincare serums

✅ Research & Lab Use

• Sample storage in controlled environments
• Long-term stability testing

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¿Por qué elegir PharGlass?

En PharGlass, we specialize in customized primary packaging solutions that meet the highest standards of quality, safety, and compliance. Our silicone and butyl rubber stoppers are manufactured using advanced molding technology and undergo rigorous testing for:

• Extractables & Leachables (E&L) profiling
• Bioburden control
• Visual inspection (no defects)
• Seal integrity testing

We support full OEM/ODM services, including:

• Custom sizing and shape
• Logo printing via hot stamping or silk screen
• COA, DMF, and technical data sheet (TDS) provision
• Fast sample delivery within 3–5 days

Whether you’re launching a new biologic drug or creating a luxury essential oil line, our stoppers ensure your product remains protected, stable, and compliant.

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📞 Contact Us Today
For pricing, technical documentation, or custom design requests — reach out to our sales team at sales@pharglass.com or visit https://www.pharglass.com.

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Note: All products are produced under cleanroom conditions and can be sterilized via gamma irradiation or autoclave upon request. We recommend chlorobutyl rubber for freeze-dried applications and white silicone for fragrance-sensitive formulations.

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